Granisetron in the treatment of obsessive-compulsive disorder
Phase 2
- Conditions
- Obsessive- Cumpulsive Disorder.Obsessive- Cumpulsive Disorder
- Registration Number
- IRCT201202041556N32
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Inclusion Criteria:Age between 18-60; Diagnosis of OCD based on DSM IV; Minimum Score of 21 on YALE-BROWN Obsessive-Compulsive Scale
Exclusion Criteria
Substance dependence; IQ <70; any other mental disorder on axis I; Any serious cardiac, renal or hepatic disease ; receiving psychotropic medications during the last 6 weeks ; pregnancy orbreast feeding; rising liver transaminases to three times the upper limit of normal or higher
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of symptoms of OCD. Timepoint: Baseline and weeks 2-4-6-8 after beginig of treatment. Method of measurement: by Y-BOCS Rating Scale.
- Secondary Outcome Measures
Name Time Method