Impact of Systematic Infants Vaccination Against Rotavirus on Gastroenteritis Hospitalization: a Prospective Study in Brest District, France.
- Conditions
- Rotavirus Gastroenteritis
- Interventions
- Biological: Rotateq vaccine
- Registration Number
- NCT00740935
- Lead Sponsor
- University Hospital, Brest
- Brief Summary
Universal rotavirus vaccination program for infants born in Brest after February 2007, applied by the Centers for Maternal and Infant Health Protection, pediatricians and general practitioners.
Prospective surveillance of hospitalizations for gastroenteritis within the Pediatric Units of Brest University Hospital with systematic testing for Rotavirus.
Evaluation of the impact of the vaccination program on rotaviral gastroenteritis hospitalizations from 2007-2008 and 2008-2009, by comparison with epidemiological data from 2002-2007 in the absence of vaccination.
The principal judgement criterion is the number of pediatric hospitalizations for rotaviral GEA during the 2008-2009 epidemic in children A) under the age of 2 and B) residing in the suburbs of Brest.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 7204
- infants aged 6 to 12 weeks
- born in Brest District, France
- born between Feb 01, 2007 and Nov 19, 2009
- contraindication to rotavirus vaccine
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description 1 Rotateq vaccine Cohort of vaccinated infants against rotavirus
- Primary Outcome Measures
Name Time Method Hospitalization for gastroenteritis 2 years
- Secondary Outcome Measures
Name Time Method Emergency department consultation for gastroenteritis 2 years
Trial Locations
- Locations (1)
Clinical Investigation Center
🇫🇷Brest, France