Effectiveness of Mouthwashes in Early Reducing the mouth Viral Load Among COVID-19 Patients

Phase 3

Recruiting

• Conditions: Early reduction in COVID-19 viral load.; Other and unspecified parts of mouth; D10.3

• Registration Number: IRCT20170117032025N7
• Lead Sponsor: Hamedan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 August 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Clinical diagnosis of COVID-19 infection based on the opinion of the treating physician based on national guidelines
Patients with mild to moderate disease

Exclusion Criteria

Patients with previous underlying oral disease
Patients with inability to properly perform the mouthwash protocol
Patients with thyroid disorders

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Early reduction of viral load in the mouth of COVID-19 patients. Timepoint: A sample of oropharyngeal swap will be taken from patients to check for viral load before intervention. Patients then use 20 cc of the appropriate mouthwash, based on the assigned group, which will be practically taught by the researcher on how to use it. After 30 minutes from the beginning of the intervention, the second sample of oropharyngeal swap will be determined to determine the virus load. After preparation, all samples will be placed in a tube containing a special medium for transmission (VTM) and will be transferred to the specialized reference laboratory COVID-19 of Hamadan University of Medical Sciences to determine the load of the virus by standard RT-PCR method. Method of measurement: A sample of an oropharyngeal swap will be taken from patients to check for viral load before intervention. After 30 minutes from the start of the intervention, a second oropharyngeal swap will be performed to determine the virus load.