Evaluation of the Effect of Pomegranate and Turmeric Mouthwash on Oral Mucositis Due to Chemotherapy

Not Applicable

• Conditions: Oral mucositis due to antineoplastic therapy.; Oral mucositis (ulcerative) due to antineoplastic therapy; K12.31

• Registration Number: IRCT20200721048159N1
• Lead Sponsor: Khoram-Abad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 April 2021

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients in the age range of 18 to 65 years
Cancer patients with chemotherapy-induced oral inflammation
Patients are able to complete a questionnaire and collaborate with the researcher
Absence of serious dental problems or teeth damaging the oral mucosa or sharp fillings
Do not use dentures
Do not use anti-inflammatory and other mouthwash solutions during research
No other systemic diseases
No history of smoking, drugs and alcohol
No oral candidiasis (fungus) or herpes simplex (virus)
Do not use cryotherapy for six weeks before the study

Exclusion Criteria

Dissatisfaction with participating in the study
Participate in another clinical trial at the same time
History of allergies to turmeric and pomegranate, lidocaine, antacids, diphenhydramine and dexamethasone
Inability of the patient to implement the treatment protocol
Patient death due to failure to respond to anticancer therapy
Combination therapies such as radiation therapy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Grade of mucositis based on WHO scale. Timepoint: Evaluation of grade of mucositis at the beginning of the study, 7 and 14 days after mouthwash containing pomegranate and turmeric extract. Method of measurement: Standard questionnaire and patient examination.