Grass Sensitisation and Allergic Rhinitis in Thai Patients
- Conditions
- Allergy to Grass PollenAllergic Rhinitis Due to Weed Pollens
- Interventions
- Other: Immunoblot
- Registration Number
- NCT01686022
- Lead Sponsor
- Mahidol University
- Brief Summary
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand. In addition, the investigators will study about the cross-reactivity among these group of allergen.
- Detailed Description
To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study.
The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- Allergic rhinitis patients age 10-50 years old
- Control: healthy volunteer age 18-50 years old
- Chronic illness such as cardiovascular diseases, liver diseases
- History of anaphylaxis
- Pregnancy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Pollen Allergy Immunoblot Pollen allergy and control will have the same intervention, ie. Skin prick test and collect serum samples.Then measure the specificIgE, immunoblot, and ELISA inhibition
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Siriraj Hospital
🇹🇭Bangkoknoi, Bangkok, Thailand