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Clinical Trials/NCT00210158
NCT00210158
Completed
Phase 2

Effects of Intraoperative Nitrous Oxide on Postoperative Pain for Patients With Current Opioid Treatment After Vertebroplasty.

Institut Bergonié1 site in 1 country39 target enrollmentJanuary 1, 2005
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ConditionsChronic Pain

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Chronic Pain
Sponsor
Institut Bergonié
Enrollment
39
Locations
1
Primary Endpoint
Post-operative Morphine Consumption
Status
Completed
Last Updated
7 months ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Peroperative opioids are known to induce N-Methyl-D-Aspartate dependent enhancement of postoperative hyperalgesia. For patients with current opioid treatment, these phenomena could be exagerated and could produce greater postoperative opioid consumption and higher pain score. Since Nitrous oxide has anti- N-Methyl-D-Aspartate properties, the aim of this study was to evaluate, in patients with current opioid treatment, the effects of peroperative Nitous oxide on postoperative opioid consumption and pain score, after vertebroplasty.

Registry
clinicaltrials.gov
Start Date
January 1, 2005
End Date
December 31, 2006
Last Updated
7 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Post-operative Morphine Consumption

Time Frame: Between surgery and up to 48 hours

Morphine consumption (mg) during PCA (Patient Controlled Analgesia)

Secondary Outcomes

  • Proportion of Participants With Post-operative Pain(Between surgery and up to 48 hours)

Study Sites (1)

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