Intraoperative Nitrous Oxide and Postoperative Pain for Patients With Current Opioid Treatment
Not Applicable
Completed
- Conditions
- Chronic Pain
- Registration Number
- NCT00210158
- Lead Sponsor
- Institut Bergonié
- Brief Summary
Peroperative opioids are known to induce N-Methyl-D-Aspartate dependent enhancement of postoperative hyperalgesia. For patients with current opioid treatment, these phenomena could be exagerated and could produce greater postoperative opioid consumption and higher pain score. Since Nitrous oxide has anti- N-Methyl-D-Aspartate properties, the aim of this study was to evaluate, in patients with current opioid treatment, the effects of peroperative Nitous oxide on postoperative opioid consumption and pain score, after vertebroplasty.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 36
Inclusion Criteria
Not provided
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Exclusion Criteria
Not provided
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Visual Analogue Scale (VAS) and morphine consumption recorded for 48 postoperative hours (every 8 hours).
- Secondary Outcome Measures
Name Time Method Preoperative and postoperative pressure pain threshold (pressure algometer)
Trial Locations
- Locations (1)
Institut Bergonié - Centre Régional de Luttre Contre le Cancer DE Bordeaux et du Sud Ouest
🇫🇷Bordeaux, France