DRKS00022991
Recruiting
Not Applicable
Immune cell profiles in the blood in children, adolescents and adults with tuberous sclerosis complex disease and their correlation with organ manifestations and treatment response to immunotherapy with mTOR inhibitors
niversitätsklinikum Münster0 sites90 target enrollmentSeptember 23, 2020
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Q85.1
- Sponsor
- niversitätsklinikum Münster
- Enrollment
- 90
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Children and adults; clinically and / or molecular\-genetic (from the blood) confirmed tuberous sclerosis with epilepsy.
- •Control group: epilepsy without evidence of tuberous sclerosis; People with no evidence of a neurological disease
Exclusion Criteria
- •Current immunotherapy except mTOR inhibitor therapy (everolimus, sirolimus) (control group of healthy people and people with epilepsy without tuberous sclerosis: also excluded when taking everolimus, sirolimus); current infection; comorbid autoimmune disease
Outcomes
Primary Outcomes
Not specified
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