DRKS00022991RecruitingNot Applicable
Immune cell profiles in the blood in children, adolescents and adults with tuberous sclerosis complex disease and their correlation with organ manifestations and treatment response to immunotherapy with mTOR inhibitors
niversitätsklinikum Münster0 sites90 target enrollmentStarted: September 23, 2020Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 90
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- one to one (—)
- Sex
- All
Inclusion Criteria
- •Children and adults; clinically and / or molecular-genetic (from the blood) confirmed tuberous sclerosis with epilepsy.
- •Control group: epilepsy without evidence of tuberous sclerosis; People with no evidence of a neurological disease
Exclusion Criteria
- •Current immunotherapy except mTOR inhibitor therapy (everolimus, sirolimus) (control group of healthy people and people with epilepsy without tuberous sclerosis: also excluded when taking everolimus, sirolimus); current infection; comorbid autoimmune disease
Investigators
Similar Trials
Recruiting
Not Applicable
Characterisation of lymphocytes in pediatric patients with inborn disorders of the immune systemD81D82Combined immunodeficienciesImmunodeficiency associated with other major defectsDRKS00032712Institut für Transplantationsdiagnostik und Zelltherapeutika (ITZ), Heinrich-Heine Universität Düsseldorf40
Not yet recruiting
Unknown
Paediatric Immune Cell Atlas: establishing an atlas of the immune system of children aged 0-18 years old.ACTRN12623000597695Children's Hospital Foundation1,600
Completed
Not Applicable
A Blood Test to Look at Cells of the Immune System in Healthy ChildrenHIV SeronegativityHIV InfectionsNCT00001109National Institute of Allergy and Infectious Diseases (NIAID)630
Completed
Not Applicable
Observational Study Describing the Immune Profile Induced By Pertussis VaccinesPertussisWhooping CoughNCT03147898Sanofi90
Not yet recruiting
Unknown
Ratio of blood cells in Under five Malnourished ChildrenCTRI/2024/06/069230niversity College of Medical Sciences
