ACTRN12623000597695尚未招募Unknown
Paediatric Immune Cell Atlas
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 入组人数
- 1,600
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- Years 至 18 Years（—）
- 性别
- All
入选标准
- •Inclusion Criteria for Healthy Cohort
- •Children aged less than 18 years old.
- •Inclusion criteria for Cardiac Surgery Cohort
- •Undergoing open cardiac surgery with sternotomy approach will be eligible for the Cardiac Surgery Cohort.
- •Meeting the same inclusion criteria as the Healthy Cohort.
- •Inclusion Criteria for Immune Disease Cohort
- •Children aged less than 18 years old who are diagnosed with immunological disease.
排除标准
- •Exclusion Criteria for Healthy Cohort
- •Subjects with known immunological disease.
- •Use of significant immune-modulating drug treatment.
- •Subjects with allergic symptoms within the last two months and/or subjects with allergies diagnosed by a qualified medical practitioner.
- •First degree relative (parent or sibling) with confirmed systemic autoimmune disease or primary immune deficiency.
- •Subjects who have been organ transplant recipients or donors.
- •Cancer or a history of cancer that is currently in remission.
- •Type 2 diabetes.
- •Known pregnancy.
- •Known infection with HIV or Hepatitis C.
- •Subjects who had a respiratory infection within the last two weeks, e.g., RSV, Influenza, SARS-CoV2, and/or flu-like symptoms for which no known causal agent could be determined.
- •Subjects with insufficient or inadequate biospecimens available for analysis.
- •Children diagnosed with other conditions, not described above, will be considered eligible for the healthy cohort. Children with suspected allergies who haven’t shown any allergic symptoms in the last 2 months can be included in the healthy cohort.
- •Exclusion criteria for Cardiac Surgery Cohort
- •Subjects with known immunological disease.
- •Use of significant immune-modulating drug treatment.
- •Subjects with allergic symptoms within the last two months and/or subjects with allergies diagnosed by a qualified medical practitioner.
- •First degree relative (parent or sibling) with confirmed systemic autoimmune disease or primary immune deficiency.
- •Subjects who have been organ transplant recipients or donors.
- •Cancer or a history of cancer that is currently in remission.
- •Type 2 diabetes.
- •Known pregnancy.
- •Known infection with HIV or Hepatitis C.
- •Subjects who had a respiratory infection within the last two weeks, e.g., RSV, Influenza, SARS-CoV2, and/or flu-like symptoms for which no known causal agent could be determined.
- •Subjects with insufficient or inadequate biospecimens available for analysis.
- •Children diagnosed with other conditions, not described above, will be considered eligible for this cohort. Children with suspected allergies who haven’t shown any allergic symptoms in the last 2 months can be included in this cohort.
- •Exclusion Criteria for Immune Disease Cohort
- •Subjects who have been organ transplant recipients or donors.
- •Cancer or a history of cancer that is currently in remission.
- •Type 2 diabetes.
- •Known pregnancy.
- •Known infection with HIV or Hepatitis C.
- •Subjects who had a respiratory infection within the last two weeks, e.g., RSV, Influenza, SARS-CoV2, and/or flu-like symptoms for which no known causal agent could be determined.
- •Subjects with insufficient or inadequate biospecimens available for analysis.
研究者
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