NCT05103813Unknown早期 1 期
Protective Effect of Beraprost Sodium Tablets on Coronary Microcirculation Function and Ventricular Remodeling After Reperfusion Therapy for Acute ST Segment Elevation Myocardial Infarction
Shenzhen People's Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2022年5月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 早期 1 期
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Major Adverse Cardiovascular Events
研究概览
简要总结
Protective effect of Beraprost Sodium Tablets on coronary microcirculation function and ventricular remodeling after reperfusion therapy for acute ST segment elevation myocardial infarction
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •It meets the diagnostic criteria of acute ST segment elevation myocardial infarction: ischemic chest pain lasts for more than 30 minutes and can not be relieved by taking nitroglycerin; ST segment elevation of ECG with two or more adjacent leads, limb lead ≥ 1mm, chest lead ≥ 2mm; Or new left bundle branch block; The serum markers of myocardial necrosis increased at least twice the normal value
- •Acute myocardial infarction was confirmed by coronary angiography
- •The clinical and angiographic data were complete
- •Direct PCI was performed within 12 hours after onset
排除标准
- •Those who do not cooperate in the inspection, have poor compliance and cannot guarantee the completion of the test
- •Conscious disorder, obvious intellectual disorder and mental disorder
- •With metal foreign bodies, such as metal prosthesis, intraocular metal foreign bodies, intracranial aneurysm clamp, etc
- •People with claustrophobia
- •Had a history of myocardial infarction, PCI and coronary artery bypass grafting
- •Factors affecting ST segment changes of ECG: complete left bundle branch block, preexcitation syndrome, pacemaker ECG, etc
研究组 & 干预措施
Beraprost Sodium Tablets
Experimental
干预措施: Beraprost Sodium Tablets (Drug)
结局指标
主要结局
Major Adverse Cardiovascular Events
时间窗: 1 year after baseline
The incidence of mace after 1 year of treatment
次要结局
未报告次要终点
研究者
研究点 (1)
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