Comparison of effect of two methods of Alveolar Recruitment Maneuvers in improving oxygenation in patients with Acute Respiratory Distress Syndrome.
- Conditions
- Health Condition 1: null- ARDS patients
- Registration Number
- CTRI/2017/09/009729
- Lead Sponsor
- KMC Hospital Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 29
All adult patients with moderate or severe stage of ARDS who requires invasive mechanical ventilation.
1. Patients age < 18 years
2. Pregnant women
3. Neurosurgical patients
4. Thoracic surgery patients
5. Patients with bronchopulmonary fistula
6. Patients with chest trauma (including lung contusion, hemothorax, or pneumothorax)
History of severe chronic obstructive pulmonary disease (had bullae or blebs visible on chest radiograph)
7. Patients who are haemodynamically unstable.
Haemodynamic instability as defined by an increase in heart rate by more than 20 beats/minute from baseline, bradycardia < 50 beats per minute; drop in systolic blood pressure exceeding 20 mm Hg from the baseline.
Desaturation (decrease by > 5% SpO2) from baseline on pulse oximetry.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Compare the improvement in oxygenation (increase in PaO2/FiO2 post application of recruitment manoeuvre) with pressure control and volume control stepwise recruitment maneuvers in Acute Respiratory Distress Syndrome.Timepoint: 30 minutes after application of recruitment maneuver
- Secondary Outcome Measures
Name Time Method Complications that can occur during application of RM compared among PCV â?? RM group and VCV â?? RM groupTimepoint: COMPLICATIONS: WITHIN 1 HOUR <br/ ><br>