Effects of Conditioning Exercises and Resistance Interval Training on Post CABG Patients.

Not Applicable

Completed

• Conditions: Coronary Artery Disease

• Registration Number: NCT06844591
• Lead Sponsor: Riphah International University

Brief Summary

Coronary artery disease (CAD) is a global health challenge influenced by diabetes, hypertension, and psychosocial stress, with women having a higher prevalence of Coronary microvascular disease. Promoting coronary collateral circulation offers an alternative coronary artery disease CAD treatment. Invasive interventions like PCI and CABG aim to enhance coronary flow, restoring blood flow to ischemic myocardium. Post-CABG challenges include depression, anxiety, and factors affecting quality of life. Physiotherapy impacts heart rate variability, with virtual reality physiotherapy reducing both heart rate variability and hospital stay. Cardiac rehabilitation involves lifestyle changes, enhancing functional capacity, and supporting early recovery. Pre-operative respiratory muscle training improves outcomes. Acute high-intensity interval exercise and mild continuous exercise benefit exercise recovery. This research compares conditioning exercises and resistance interval training effects on post-CABG patients' well-being.

Detailed Description

The randomized clinical trial will be conducted in physical therapy department at the District Headquarters (DHQ) in Gujranwala, employing a non-probability convenience sampling technique. The study aims to include individuals aged 40-55 years. Participants in phase IV cardiac rehabilitation. Both female and male will be included.Exclusion criteria involve individuals with another clinical trial involving physical protocols. Regular practice of physical exercise of more than 150min per week in last 3 months. Decompensated heart failure. Further exclusions encompass individuals who have had an acute myocardial infarction or cardiac surgery within the last 6 months, severe valvular heart diseases, uncontrolled cardiac arrhythmias, asymmetric septal hypertrophic cardiomyopathy with dynamic obstruction in the outflow pathway, musculoskeletal disorders limiting completion of the exercise program, and impaired cognitive status affecting understanding and adherence to the study protocol. Group A will be given a Conditioning exercise protocol while the other Group B will be given resistance interval training. The difference in improvement before and after 6 weeks will be documented and compared.

Study Timeline

• Study Start: 2024-03-09
• Primary Completion: 2024-05-30
• Study Completion: 2025-01-15
• Status Verified: 2025-02
• Study First Submitted: 2025-02-20
• Study First Submitted QC: 2025-02-24
• Last Update Submitted: 2025-02-24
• Study First Posted: 2025-02-25
• Last Update Posted: 2025-02-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• age 40-55 years
• post-coronary artery bypass graft (CABG) patients both females and males were included
• New York Heart Association criteria IV
• Hemodynamically stable patient

Exclusion Criteria

• Fall in New York Heart Association criteria II III;
• Hemoglobin < 9 g/dL;
• Patients with peripheral or vascular problems of the lower limb,
• Cognitive and/or mental disorders;
• Exercise limiting comorbidities (primarily orthopedic, neurological condition)
• Enrollment in another clinical trial involving physical training protocols.
• Not willing to participate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
SF-36 Questionnaire	6 weeks	The 36-Item Short Form Survey (SF-36) is an outcome measure instrument that is often used for quality of life, well-researched, self-reported measure of health. It stems from a study called the Medical Outcomes Study for the objective measure of the quality of life. The 36-Item Short Form Survey (SF-36) will be used which is a self-reported measure of health that covers eight domains of health.
6-minute walk test	6 weeks	The 6-minute walk test (6MWT) will be used for cardiorespiratory fitness, to measure the distance walked in a specified time and reflect the functional exercise level. The primary measurement is 6-min walk distance (6MWD), but during the 6MWT data can also be collected about the patient's blood oxygen saturation and perception of dyspnea during exertion. When conducting the 6MWT do not walk with the patient and do not assist the patient in carrying or pulling his or her supplemental oxygen. The patient should walk alone, not with other patients. Do not use a treadmill on which the patient adjusts the speed and/or the slope. Do not use an oval or circular track. An increase in the distance walked indicates improvement in basic mobility. Post training a difference of at least 45m should be observed for the 6 minutes' walk test to be sure that a "real" change in the patient's condition
30-second stand chair	6 Weeks	For endurance, the sit-to-stand (STS) test measures the number of times a person can stand up from a chair in a given time (30 seconds, 1 minute, or 5 repetitions). The 30 Second Sit to Stand Test is also known as 30 Second Chair Stand Test (30CST), was initially designed for testing leg strength and endurance in adults. The score is the total number of stands within 30 seconds (more than halfway up at the end of 30 seconds counts as a full stand).The 30-second chair stand involves recording the number of stands a person can complete in 30 seconds rather then the amount of time it takes to complete a pre- determined number of repetitions.

Trial Locations

Locations (1)

Cheema Heart complex, Hospital Gujranwala; 🇵🇰 Gujrānwāla, Punjab, Pakistan