The effect of short-term co-administration of folate on aggressive behaviors in Attention Deficit Hyperactivity Disorder
Phase 2
- Conditions
- Attention Deficit Hyperactivity Disorder (ADHD).Hyperkinetic disorders
- Registration Number
- IRCT201108193930N11
- Lead Sponsor
- Vice chancellor for research, Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Diagnosis of Attention Deficit Hyperactivity Disorder (ADHD) according to DSM-IV diagnostic criteria; children and adolescents aged 7 to 19 years old. Exclusion criteria: Self reported an allergic reaction to folic acid; kidney disease; being on dialysis; infection; anemia; epilepsy; taking medications such as phenytoin, methotrexate, nitrofurantoin, tetracycline barbiturates such as Phenobarbital, primidone; lack of providing written informed consent for participation; a diagnosed psychotic disorder; extensive use of nutritional folic acid supplements within the previous 3 months; behavior therapy or any other psychotherapy in the last three months or during this study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ADHD rating questionnaire. Timepoint: evey 30 days. Method of measurement: parent report.
- Secondary Outcome Measures
Name Time Method Modified Overt Aggression Scale. Timepoint: evey 30 days. Method of measurement: parent report.