Assessment of Zinc Absorption From a Phytic Acid Rich Complementary Food

Completed

• Conditions: Bioavailability

• Registration Number: NCT01506648
• Lead Sponsor: Swiss Federal Institute of Technology

Brief Summary

Assessment of zinc absorption from a phytic acid rich complementary food, consumed by young children immediately after the addition of the enzyme phytase. A randomized single blind study

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01
• Study First Submitted: 2012-01-09
• Study First Submitted QC: 2012-01-09
• Study First Posted: 2012-01-10
• Primary Completion: 2012-04
• Study Completion: 2012-10
• Status Verified: 2016-11
• Last Update Submitted: 2016-11-25
• Last Update Posted: 2016-11-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. 12-24 month old
2. Male of female
3. Height and weight between -2.0 SD and +2.0 SD with respect to WHO child growth standards.
4. No mineral and vitamin supplements 2 weeks prior to the study and during the whole duration of the study

Exclusion Criteria

1. Body temperature ≥ 37.5°C
2. Hemoglobin ≤ 7g/dL
3. Positive RDT test
4. Any metabolic, gastrointestinal or chronic disease (according to the statement of the subject's parent) known chronic diseases at the gastrointestinal tract)
5. Long term mediation (that may affect zinc metabolism) during the whole study to interact with zinc metabolism (such as kidney diseases or

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fractional absorption of zinc	33 days	Fractional absorption of zinc is estimated by using the double isotope tracer ratio technique by administering 67Zn as oral and 70Zn as intravenous stable isotopes.The urinary enrichment with both isotopes is measured in a spot urine sample by inductively coupled plasma mass spectrometry.

Trial Locations

Locations (1)

CHU-Yalgado Ouédraogo, Service Pédiatrie; 🇧🇫 Ouagadougou, Burkina Faso