Comparison between two drugs for pain relief after spine surgery

Phase 4

Not yet recruiting

• Registration Number: CTRI/2025/06/088680
• Lead Sponsor: Smt.Bhikiben Kanjibhai Shah Medical Institute and Research Centre

Brief Summary

This randomised comparative study aims to evaluate the efficacy of dexmedetomidine versus dexamethasone as adjuvants to 0.375% ropivacaine in erector spinae plane (ESP) block for patients undergoing lumbar spine surgery under general anaesthesia. The study focuses on assessing both intraoperative and postoperative pain control, comparing parameters such as duration of analgesia, total analgesic consumption, haemodynamic stability, and incidence of side effects. By identifying the more effective adjuvant, this research seeks to enhance patient comfort and improve pain management strategies in lumbar spine surgeries.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-01-07
• Last Update Posted: 2025-12-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients willing to participate in the study, Patients of ASA grade I, II, III of either gender, Patients undergoing elective lumbar surgery , Age of patients 18-75 years.

Exclusion Criteria

Patients refusal, Patient belonging to ASA IV, V GRADE , Patients with bleeding and coagulation disorders, Infection at the site.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the efficacy of dexmedetomidine with 0.375%ropivacaine vs dexamethasone with 0.375%ropivacaine in erector spinae block in lumbar spine surgery under general anaesthesia for intraoperative and postoperative pain management.	one hourly for next 24hours post operatively

Secondary Outcome Measures

Name	Time	Method
The study focuses on assessing both intraoperative & postoperative pain control, comparing parameters such as duration of analgesia, total analgesic consumption, haemodynamic stability, & incidence of side effects.	hourly for next 24hours postoperatively

Trial Locations

Locations (1)

Smt.Bhikiben Kanjibhai Shah Medical Institute and Research Centre; 🇮🇳 Vadodara, GUJARAT, India

Smt.Bhikiben Kanjibhai Shah Medical Institute and Research Centre

🇮🇳Vadodara, GUJARAT, India

D R Binay Teja Reddy

Principal investigator

9182420631

binayteja15@gmail.com