High-concentration Small-volume Versus Low-concentration Large-volume Iodine Solution for Esophageal Chromoendoscopy
- Conditions
- Esophageal Squamous Cell Carcinoma
- Registration Number
- NCT06063941
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 450
Inclusion Criteria:<br><br> - Patients undergoing esophageal Lugol's iodine chromoendoscopy.<br><br> - Age = 18<br><br>Exclusion Criteria:<br><br> - Patients allergic to iodine or with hyperthyroidism;<br><br> - Patients with esophageal varices, esophageal ulcer or other conditions inadvisable<br> for Lugol chromoendoscopy;<br><br> - Patients with severe gastroesophageal reflux disease or reflux symptoms which may<br> interfered with the outcome measures of current study;<br><br> - Patients with postoperative esophageal stenosis affecting endoscopic observation;<br><br> - Patients who could not cooperate with the observation and data collection including<br> patients with mental disorders, severe neurosis, dysgnosia or communication<br> disorder;<br><br> - Patients with advanced-stage tumors;<br><br> - Patients after upper gastrointestinal surgery;<br><br> - Patients who do not agree to sign informed consent forms or follow the trial<br> requirement.
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Visual analogue scale scores at 30 minutes after chromoendoscopy
- Secondary Outcome Measures
Name Time Method The color objective evaluation after chromoendoscopy;The color subjective evaluation after chromoendoscopy;Heart rate variability;The incidence rate of the need for additional iodine solution spraying;The dosage of additional iodine spraying;Visual analogue scale scores at 5 minutes after chromoendoscopy;The incidence rate of esophageal spasms;The incidence rate of adverse incidents;The incidence rate of upper abdominal discomfort or pain.;Associated factors for visual analogue scale scores