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临床试验/CTRI/2025/08/092236
CTRI/2025/08/092236招募中3 期

Study of efficacy of Doshahara Basti in Upasthambita Vata Vyadhis - A case series

Sushrutha Ayurvedic Medical College and Hospital1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2025年8月13日最近更新:

试验速览

阶段
3 期
状态
招募中
发起方
入组人数
10
试验地点
1
主要终点
Efiicacy of Doshahara Basti

研究概览

简要总结

Need of the study:

·       Good health needs following of regular Dinacharya, Ratricharya and Ritucharya of Ayurveda Science. The main aim is “Swasthyashya Swasthya Rakshanam, Athurasya Roga Prashamanam”. External environmental changes have the impact on the human body to disturb the equilibrium of the Doshas i.e. Dosha Vaishamya, if body is unable to adopt itself to stressors due to changes in specific traits of seasons. Ayurveda accepts if we keep the pearl in pure water for a longer period, there is the chances of deposition of mud in it. In the same way for healthy individual also there may be the chances of Dosha Vaishamya during the seasonal changes. Hence to overcome this condition a beautiful concept like Ritu Shodhana (Seasonal Purification) mentioned in Ayuredic life Sceince which plays a vital role for the prevention of diseases. In present scenario due to busy schedule and irregular diet habits, excess use of fast food, lack of physical activities, over stress people leads to production Ama in the body which results in Avarodhajanita Vata Vyadhis. i.e. Upastambita Vata Vyadhis in Ayurveda. This comes under the 80 types of Vata Vyadhi. Present study deals with Upastambita Vata Vyadhis like Kaphanubandhi Pakshagata,Kapha Vataja Apabahuka, Kapha Vataja Gridrasi, ManyaSthamba etc.

·       Varsha Ritu - Mid-July to Mid-September, is the beginning season of Visarga Kaala, in which vitiation of all the three Doshas, Specifically Vata Dosha and also depletion of agni leading to aggravation of all those amaja conditions.

·       Basti is the line of treatment in Varsha Ritu. Hence an effort has been made to access the role of Doshahara Basti in above conditions during Varsha ritu as Ritu Shodhana.

 ·       The ingredients of Doshahara basti like Madhu and Sneha – Guggulu Tiktaka Ghrita, Erandamoola Kwatha along with Saindhava, Rasna, Devadaru, Hingu, Vacha, Shatahava has Amapachaka and as well as Vatanashaka effect, so this study is planned.

 Primary Objective:

q To assess the effect of Varshika Basti on Upasthambita Vata Vyadhi

Secondary Objective:

q To assess the efficacy of Doshahara Basti in Upasthambita Vata Vyadhi

 Materials & Methods:

u      Study Type    : Clinical Pilot study

u      Level of study:  Out-patient Department (OPD) and In-patient Department (IPD) of SAMC&H

u      End Point        : Efficacy and Safety.

u      No. of Groups  : One

u      Sample Size     : 10  subjects

 Inclusion Criteria:

·       Aged between 18 – 60 Years.

·       Diagnosed cases of Upathambita Vatavyadhis of either sex will be taken.

·       Basti Yogyas

Exclusion Criteria:

·       Basti Ayogyas

·       Individuals suffering from Chronic diseases and complications, those who have underwent major surgical procedures.

·       Pregnant ladies & lactating women

Treatment Interventions:

Administration method will be followed as per the classical text.

Form: Doshahara Basti – Niruha ingredients

Madhu- 100ml (2 pala)

Saindhava- 10gms (1/2 karsha)

Sneha (Guggulu tikitaka Ghrita) - 100ml (2 pala)

Kalka (Shatahva) - 30gms (3 karsha)

Kwatha (Erandamoola, Rasna, Shatapushpa, Vacha, Hingu, Devadaru) - 350ml

(8pala)

Anuvasana – Guggulu Tiktaka Ghrita

 o  Dose                               : Niruha Basti – 570ml

Anuvasana Basti (Guggulu Tikitaka Ghrita) – 80ml

o  Route of Administration : Anal route

o  Time of Administration : Niruha - Before food, Anuvasana – After food

o  Duration of therapy         :Yoga Basti (8 days)

Assessment Criteria: Subjective

Subjective

Upastambita vatvyadhi Lakshana

Vibandh

Bahuvedana

Asthi-parva Stambh

Sankoch

Gourava

Tandra

Shotha

Sparshasahatwa

Ushna sparsh

Daha

Bheda,Toda

Arti,

Ayasa

Agnisada

Snehasyadi Vruddhi

Jwara

 Scoring: No, mild, moderate, severe grading’s will be used from 0-4

 Objective

Lab investigation – CBC, ESR, CRP

Assessment duration:

Before treatment, at the end of the treatment i.e., on 8th day, after 16 days of treatment i.e. 24th day (Dwi Parihara Kala according to Charaka)

 Statistical analysis: paired T test

Conclusion:

·       Present aim of the study is to evaluate “Effect of Varshika Basti in Upastambita Vata Vyadhis – A case series w.s.r Doshahara Basti”

·       In Varsha Ritu all three doshas get vitiated, specifically vata. There in impairment in agni leading to Amajanita Vata Vyadhis if not followed proper diet and regimens.

·       As the selected ayurvedic prepration is Doshahara basti – most of the dravyas have Tridosha Hara properties, improves Agni, and removes Ama which helps to show its positive effect on Upasthambita Vata Vyadhis as a part of Ritu Shodhana.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • • Diagnosed cases of Upathambita Vatavyadhis like Manyastamba Apabahuka Kaphaja Gridrasi etc of either sex will be taken.
  • • Patients fit for Basti Procedure according to classics.

排除标准

  • • Patients not fir for Basti • Individuals suffering from Chronic diseases and complications, those who have underwent major surgical procedures.
  • • Pregnant ladies & lactating women.

结局指标

主要结局

Efiicacy of Doshahara Basti

时间窗: 0 day | 8th day | 16th day

on subjective parameters and objective parameters

时间窗: 0 day | 8th day | 16th day

次要结局

未报告次要终点

研究者

发起方
Sushrutha Ayurvedic Medical College and Hospital
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Sanghamitra Patnaik

Sushrutha Ayurvedic Medical College and Hospital

研究点 (1)

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