Effect of Resistance Training Variable Manipulation (Intensity and Volume) on Body Composition, Fatigability and Functional Capacity in Postmenopausal Breast Cancer Survivors.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Breast Cancer Survivors
- Sponsor
- Universidade Federal do Triangulo Mineiro
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Evaluation the Fatigability
- Last Updated
- 7 years ago
Overview
Brief Summary
This study intends to evaluate the impact of resistance training variable manipulation (intensity and volume) on body composition, fatigability and functional capacity in postmenopausal breast cancer survivors.
Detailed Description
The treatment for breast cancer (chemotherapy, radiotherapy and hormone therapy) provokes collateral effects,such as muscle mass and strength losses, increase of fat mass, fatigue and disability and reduced quality of life in postmenopausal breast cancer survivors. The resistance training is assumed as a non-pharmacologic interventions in postmenopausal breast cancer survivors. However, it is unclear whether the manipulation of training variables (intensity and volume) maximize the effects of resistance training on body composition, fatigability and functional capacity in postmenopausal breast cancer survivors.
Investigators
Fábio Lera Orsatti
Principal Investigator
Universidade Federal do Triangulo Mineiro
Eligibility Criteria
Inclusion Criteria
- •Postmenopausal breast cancer survivors;
- •No supervised or unsupervised exercise at least for six months prior to the study.
Exclusion Criteria
- •Alcoholics;
- •No controlled blood pressure and glucose;
- •Presence of myopathies, arthropathies, and neuropathies;
- •Presence of muscle, thromboembolic and gastrointestinal disorders, infection diseases.
Outcomes
Primary Outcomes
Evaluation the Fatigability
Time Frame: pre and post intervention (i.e. 12 weeks)
The fatigability will be evaluate by 60 maximum voluntary isometric contractions (3 s contraction, 2 s rest) in knee extensors at 70 degree
Secondary Outcomes
- Four- meter walk test(pre and post intervention (i.e. 12 weeks))
- Six Minutes-walk test (6MWT)(pre and post intervention (i.e. 12 weeks))
- Timed Up and Go test(pre and post intervention (i.e. 12 weeks))
- Fat mass(pre intervention and post intervention (i.e. 12 weeks))
- 10-meter walk test(pre and post intervention (i.e. 12 weeks))
- 400-meter walk test(pre and post intervention (i.e. 12 weeks))
- 900-meter walk test(pre and post intervention (i.e. 12 weeks))
- Muscle mass(pre and post intervention (i.e. 12 weeks))
- Muscle strength(pre and post intervention (i.e. 12 weeks))
- Five-times-sit-to-stand test(pre and post intervention (i.e. 12 weeks))