Delirium and blood glucose in older patients undergoing hip surgery

Completed

Conditions: glucose variability
mean absolute glucose change
10018424
10012221

Registration Number: NL-OMON41505

Lead Sponsor: Tergooi

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 145

Inclusion Criteria

Age 70 years or older.
Admitted to the Geriatric trauma unit or to the department of Orthopaedics for hip surgery.
An increased risk for the development of delirium using the Tergooi questionaire based on the Safety Management System theme 'vulerable older patients'.
Inclusion within 24 hours after hospital admission.
The patient speaks either Dutch or English.
Patient must be able to give written informed consent.

Exclusion Criteria

Patients presenting with a diminished capacity to consent at admission.
Patients with a diagnose of diabetes mellitus and/ or treated with oral antidiabetic drugs or insulin.
Patients who are fed with parenteral nutrition during their hospital stay.
Patients who are enrolled in a study with a medicinal product.

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Mean absolute glucose change per hour (mmol/l/hour)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-The mean glucose concentration.<br /><br>-Glucose variability: standard devation of the mean glucose concentration and<br /><br>coefficient of variation and the mean glucose daily delta change<br /><br>- The presence of an isolated hypoglycemia or hyperglycemia.<br /><br><br /><br>Potential risk factors:<br /><br>1. Age 2. Gender 3. Body mass index 4. Cigarette smoking 5. Alcohol consumption<br /><br>6. Introduction of diabetes mellituis treatment<br /><br>7. Number of glucose influencing drugs. 8. Insulin concentration 9. Occurrence<br /><br>of a delirium. 10.Treatment with antipsychotic drugs. 11. Occurrence of any<br /><br>infection. 12. Nutrition. 13. Vitamin D concentration 14.Pain 15. Iron status<br /><br>16. Serum triglycerides<br /><br>17. Blood coagulation<br /><br><br /><br>- Length of hospital admission<br /><br>- 6- months and 1 year mortality</p><br>