Hepcidin and Anaemia in Pregnancy (HAPn)
Not Applicable
Completed
- Conditions
- Pregnancy and ChildbirthAnaemia in pregnancy
- Registration Number
- ISRCTN21955180
- Lead Sponsor
- The Medical Research Council (MRC) (UK)
- Brief Summary
1. 2016 protocol in: https://www.ncbi.nlm.nih.gov/pubmed/27411564 2. 2019 results in https://www.ncbi.nlm.nih.gov/pubmed/31607468 (added 15/10/2019)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 498
Inclusion Criteria
1. Pregnant (gestational age between 14 - 22 weeks)
2. Age: 18 to 45 years
3. Likely to be resident in study area for duration of trial
4. Written informed consent obtained
Exclusion Criteria
1. Severely anaemic (< 7 g/dl)
2. Seriously ill (infectious disease of clinical significance) at recruitment
3. Chronic disease
4. Pregnancy complications (e.g. pre-eclampsia) at enrolment
5. Already part of another study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Haemoglobin - defined as pregnancy stage adjusted haemoglobin at day 84
- Secondary Outcome Measures
Name Time Method <br> 1. Proportion of anaemia (Hb < 11 g/dl) at day 84<br> 2. Iron deficiency prevalence at day 84<br> 3. Iron deficiency anaemia (IDA) prevalence at day 84<br> 4. Iron dosage<br> 5. Beneficial and adverse events<br> 6. Compliance<br>