Branched-chain Amino Acids Supplementation and Resistance Exercise-induced Muscle Damage and Inflammation

Not Applicable

Suspended

• Conditions: Inflammation; Muscle Damage
• Interventions: Dietary Supplement: Leucine; Dietary Supplement: Placebo; Dietary Supplement: BCAA

• Registration Number: NCT01305018
• Lead Sponsor: University of Sao Paulo

Brief Summary

This study aims to evaluate the effects of branched-chain amino acids (BCAA) supplementation on resistance exercise-induced muscle damage and inflammation.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-02-25
• Study First Submitted QC: 2011-02-25
• Study First Posted: 2011-02-28
• Status Verified: 2011-04
• Last Update Submitted: 2011-05-04
• Last Update Posted: 2011-05-05
• Study Start: 2011-08
• Primary Completion: 2012-01
• Study Completion: 2012-08

Recruitment & Eligibility

• Status: SUSPENDED
• Sex: Male
• Target Recruitment: 30

Inclusion Criteria

• Sedentary;
• No muscle disorders;
• Must be able to swallow tablets

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Exercise and Leucine	Leucine	-
Exercise and Placebo	Placebo	-
Exercise and BCAA	BCAA	-

Primary Outcome Measures

Name	Time	Method
Muscle edema	4 days
Muscle soreness	4 days
Muscle maximal strength	4 days

Secondary Outcome Measures

Name	Time	Method
Muscle damage	4 days	Serum creatine kinase
Muscle inflammation	4 days	Immunohistochemistry, protein expression.

Trial Locations

Locations (1)

University of São Paulo - School of Physical Education and Sports; 🇧🇷 São Paulo, Brazil