A prospective study of the aetiology and detection of fluid overload and oedema in critically ill children

The Royal Children's Hospital0 个研究点目标入组 100 人开始时间: 2021年5月12日最近更新: 2021年7月5日

试验速览

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•1.Mechanically ventilated at enrolment or expected to be intubated upon elective PICU admission
•2.Admitted to the PICU within previous 72 hours
•3.Expected to be mechanically ventilated until the day after tomorrow
•4.Expected to have arterial or venous access for 48 hours after enrolment
•5.Can be safely and accurately weighed

•1.Unable to be weighed safely (haemodynamic instability, traumatic brain injury and unstable intracranial pressure, unsecured spinal injury, severe orthopaedic injuries, insecure endotracheal tube)
•2.Children expected to stay in PICU less than 48 hours
•3.Cerebral venous obstruction/proximal upper limb, upper leg venous obstruction or thrombosis/ cavo- pulmonary shunt
•4.Ocular/facial injury/Surgery
•5.Inability to lie supine in a fixed position
•6.Prone positioning in the 6 hours prior to enrolment
•7.Known protein losing states – e.g. Nephrotic syndrome, protein losing enteropathy, lymphangiectasia
•8.Prior enrolment in the same study
•9.Expected weight > 65 kg
•10.COVID-19 positive or clinical suspicion of COVID-19

发起方