CTRI/2019/04/018349尚未招募3 期
Efficacy and tolerability of plasma exchange in patients with alcohol related acute on chronic liver failure-a pilot study
Rekha Hans0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1.Age more than 18 years
- •2.First episode of de-compensation with APASL ACLF Research Consortium (AARC)- ACLF grade I or II (AARC score <=10)
- •3.Cause of ACLF being alcohol related liver disease
- •4.No evidence of active infection
- •5.Willing to give informed consent for the procedure(In patients who are incompetent to consent,consent shall be taken from the surrogate)
排除标准
- •1.Pregnancy
- •2.Causes of ACLF other than alcohol
- •3.Co-existing HCC or extra-hepatic malignancy
- •4.Microbiological or radiological evidence of active infection
- •5.Active hemorrhage
- •6.Extra-hepatic multi-organ failure (>=3 organ failures)
- •7.APASL-AARC score >10
- •8.Known allergy to Plasma, Protamine or Heparin.
- •9.Mechanically ventilated patients
- •10.Severe preexisting cardiopulmonary disease
- •11.Requiring inotropic support
- •12.Renal failure requiring dialysis
- •13.Severe systemic illness like HIV
- •14.Post liver transplant patients
- •15.Death within 24 hours of presentation
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