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Clinical Trials/CTRI/2019/04/018349
CTRI/2019/04/018349
Not yet recruiting
Phase 3

Efficacy and tolerability of plasma exchange in patients with alcohol related acute on chronic liver failure-a pilot study

Rekha Hans0 sites0 target enrollmentTBD
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ConditionsHealth Condition 1: K704- Alcoholic hepatic failure

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Health Condition 1: K704- Alcoholic hepatic failure
Sponsor
Rekha Hans
Status
Not yet recruiting
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
Rekha Hans

Eligibility Criteria

Inclusion Criteria

  • •1\.Age more than 18 years
  • •2\.First episode of de\-compensation with APASL ACLF Research Consortium (AARC)\- ACLF grade I or II (AARC score \<\=10\)
  • •3\.Cause of ACLF being alcohol related liver disease
  • •4\.No evidence of active infection
  • •5\.Willing to give informed consent for the procedure(In patients who are incompetent to consent,consent shall be taken from the surrogate)

Exclusion Criteria

  • •1\.Pregnancy
  • •2\.Causes of ACLF other than alcohol
  • •3\.Co\-existing HCC or extra\-hepatic malignancy
  • •4\.Microbiological or radiological evidence of active infection
  • •5\.Active hemorrhage
  • •6\.Extra\-hepatic multi\-organ failure (\>\=3 organ failures)
  • •7\.APASL\-AARC score \>10
  • •8\.Known allergy to Plasma, Protamine or Heparin.
  • •9\.Mechanically ventilated patients
  • •10\.Severe preexisting cardiopulmonary disease

Outcomes

Primary Outcomes

Not specified

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