Comparison of Endometrial Protein Profile in Spontaneous Versus Stimulated Menstrual Cycles in Poor Responders

Not Applicable

Completed

• Conditions: Proteome

• Registration Number: NCT06804174
• Lead Sponsor: University Medical Centre Ljubljana

Brief Summary

Evaluation of endometrial protein profile in spontaneous and stimulated menstrual cycles

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-01
• Primary Completion: 2024-06-30
• Study Completion: 2024-09-01
• Status Verified: 2024-10
• Study First Submitted: 2025-01-27
• Study First Submitted QC: 2025-01-27
• Last Update Submitted: 2025-01-27
• Study First Posted: 2025-02-03
• Last Update Posted: 2025-02-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 15

Inclusion Criteria

1. Primary infertility
2. Poor ovarian response

Exclusion Criteria

1. Normal or high ovarian response to gonadotropin stimulation
2. Menstrual cycle disorders
3. Severe male cause of infertility
4. Preimplantation genetic testing
5. Pathological findings of the uterus (fibroids, endometrial polyps, adenomyosis) and fallopian tubes (distal occlusion of one or both fallopian tubes with hydrosalpinx).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Analysis of endometrial proteome after the use of gonadotropins	From enrollment to the end of treatment (approximately 2 months).	Comparison of endometrial proteome during the window of implantation between spontaneous and stimulated cycles.

Trial Locations

Locations (1)

Division of Obstetrics and Gynecology, university Medical Centre Ljubljana; 🇸🇮 Ljubljana, Slovenia