A Clinical Model for Dialysis Discontinuation in AKI

Completed

• Conditions: Acute Kidney Injury; Acute Renal Failure

• Registration Number: NCT06005896
• Lead Sponsor: University of Sao Paulo General Hospital

Brief Summary

A retrospective study evaluating AKI patients in whom RRT was interrupted for at least 48 hours. Patients who were still RRT-independent 7 days after initial RRT cessation were included in the "Success" group, as opposed to the "Failure" group. Baseline characteristics and variables at the time of RRT interruption were collected. Multivariable analysis was performed and a model was generated to evaluate the prediction of success.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-01
• Primary Completion: 2022-02-01
• Study Completion: 2022-02-01
• Status Verified: 2023-08
• Study First Submitted: 2023-08-16
• Study First Submitted QC: 2023-08-16
• Last Update Submitted: 2023-08-16
• Study First Posted: 2023-08-23
• Last Update Posted: 2023-08-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 124

Inclusion Criteria

• All patients receiving kidney replacement therapy due to AKI from October 2020 to February 2022 were considered for inclusion in the study. Patients who managed to remain at least 48 consecutive hours without receiving kidney replacement therapy prescription were included.

Exclusion Criteria

• Patients who had kidney replacement therapy interrupted exclusively due to haemodynamic instability, death or decision for palliative care were excluded.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Success in RRT discontinuation	7 days	To be alive and free from RRT 7 days after interrupting RRT.

Trial Locations

Locations (1)

University of São Paulo School of Medicine; 🇧🇷 São Paulo, SP, Brazil