The effect of zinc supplementation on young women with premenstrual syndrome
Phase 3
Recruiting
- Conditions
- premenstrual syndrome.Premenstrual tension syndrome
- Registration Number
- IRCT20180215038738N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
18.5 < Body mass index (BMI) < 25
single women
regular menstrual cycle of 21-35 days
Exclusion Criteria
taking any medications containing estrogen and progesterone
taking zinc supplement in past 3 months
exercising regularly
being depressed or having anxiety
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Physical symptoms of young women with premenstrual syndrome. Timepoint: before and 12 weeks after the start of intervention. Method of measurement: daily record questionnaire.;Psychological symptoms of young women with premenstrual syndrome. Timepoint: before and 12 weeks after the start of intervention. Method of measurement: daily record questionnaire.;Total antioxidant capacity. Timepoint: before and 12 weeks after the start of intervention. Method of measurement: Laboratory analysis ( blood test).;Serum concentrations of Brain derived neurotrophic factor. Timepoint: before and 12 weeks after the start of intervention. Method of measurement: Laboratory analysis ( blood test).;Serum concentrations of high-sensitivity C-reactive protein. Timepoint: before and 12 weeks after the start of intervention. Method of measurement: Laboratory analysis ( blood test).;Serum concentrations of zinc. Timepoint: before and 12 weeks after the start of intervention. Method of measurement: Laboratory analysis ( blood test).
- Secondary Outcome Measures
Name Time Method Sleep quality. Timepoint: before and 12 weeks after the start of intervention. Method of measurement: pittsburgh sleep quality index.;Quality of life. Timepoint: before and 12 weeks after the start of intervention. Method of measurement: World Health Organization Quality Of Life questionnaire.