Randomised controlled study of 'physiological' peritoneal dialysis solutions

Not Applicable

Completed

• Conditions: rological and Genital Diseases: Peritoneal dialysis; Urological and Genital Diseases; Peritoneal dialysis

• Registration Number: ISRCTN37099489
• Lead Sponsor: Record Provided by the NHSTCT Register - 2007 Update - Department of Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-09-28
• Study Completion: 2013-04-29
• Last Update Posted: 30 April 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 131

Inclusion Criteria

All patients selected to use a PD system that has physiological and standard solutions available

Exclusion Criteria

1. Patients unable to provide informed consent
2. Patients where the use of a certain solution is indicated or contra-indicated for medical reasons (eg known allergy)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patients using physiological solutions will have lower peritonitis rate than control group.

Secondary Outcome Measures

Name	Time	Method
1. Patients using physiological solutions will have better preservation of residual kidney function<br>2. Patients using physiological solutions will have smaller changes in peritoneal membrane function assessed by PET than control group<br>3. Patients using physiological solutions will have reduced composite end-point of mortality and PD failure defined by transfer to HD in patients using physiological solutions