ow dose prednisolone regimen for treatment of relapses in nephrotic syndrome
Not Applicable
- Conditions
- Health Condition 1: null- Steroid sensitive nephrotic syndrome in relapase
- Registration Number
- CTRI/2017/11/010376
- Lead Sponsor
- Maulana Azad Medical College and associated Lok Nayak Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All children and adolescents who are known cases of steroid sensitive nephrotic syndrome (infrequent relapsers, frequent relapsers, steroid dependent who have received alternate agents in the past) presenting with a relapse.
Exclusion Criteria
•Children and adolescents with serious infections(sepsis, meningitis, peritonitis)
•Children and adolescent swith steroid resistant nephrotic syndrome
•Children and adolescents receiving stress doses of steroids
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effectiveness of low dose prednisolone regimen and standard therapy in maintaining remission at the end of therapy <br/ ><br> <br/ ><br>Timepoint: 2 weeks, 4 weeks after initiating therapy and then every month for next 3 months.
- Secondary Outcome Measures
Name Time Method â?¢Mean Time to remission in each group <br/ ><br>â?¢Steroid doses received in past 6 months <br/ ><br>â?¢Relapse at 1 month and 3month follow up <br/ ><br>Timepoint: 2 weeks, 4 weeks after initiating therapy and then every month for next 3 months.