Prone Fluid Responsiveness in Children
- Conditions
- Pediatric ALL
- Interventions
- Procedure: TVC
- Registration Number
- NCT05449886
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
In pediatric patients in the prone position, the reliability of pulse pressure variation and stroke volume variation, and pleth variability index to predict fluid responsiveness have not previously been established. Perioperatively, in this setting, optimizing fluid management can be challenging, and fluid overload is associated with both intraoperative and postoperative complications. The investigator designed this study to assess the sensitivity and specificity of baseline PPV, SVV, and PVI the tidal volume (VT) challenge (VTC) and in predicting fluid responsiveness during elective neurosurgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 40
- elective neurosurgery and requiring prone positioning
- (1) chronic cardiac arrhythmia; (2) depressed left (<30% of ejection fraction) (3) patients with pulmonary disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Tidal volume challenge TVC -
- Primary Outcome Measures
Name Time Method fluid responsiveness prediction using AUC of ROC curve analysis from induction of anesthesia to end of operation, about 5 hours stroke volume index increase more than 10% from baseline after volume administration (10ml/kg) Fluid responsiveness parameters; PPV, SVV, PVI, rPVI before and after tidal volume challenge
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hee-Soo Kim
🇰🇷Seoul, Korea, Republic of