Effect of methotrexate on Thyroid function in Rheumatoid Arthritis Patients of Uttarakhand Region of India
Not Applicable
- Conditions
- Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- CTRI/2024/07/069997
- Lead Sponsor
- Dr Mahima Gupta
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All Patients of RA of age 18 years or more who are managed with methotrexate for = one year
Exclusion Criteria
Patient already having thyroid disease at the time of diagnosis of rheumatoid arthritis
Pregnant patients
Patient on drugs affecting thyroid function
Patients undergone surgery or radiation around neck area
Patient having any hypothalamo-pituitary disorder/disease
Patients not willing to give consent.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To estimate the proportion of patients with altered thyroid profiles among the patients of Rheumatoid arthritis who were taking methotrexate for = 1 yearTimepoint: duration of study is 1 year
- Secondary Outcome Measures
Name Time Method To evaluate the association of thyroid profile with different durations of methotrexate use. <br/ ><br>To evaluate the association of thyroid profile with different add on drugs in Rheumatoid arthritis management. <br/ ><br>To examine the Adverse Drug Reaction arising from anti-rheumatoid drug treatment <br/ ><br>Timepoint: duration of study is 1 year