Assessment of Brain Activity Change in Computerized Cognitive Rehabilitation Program in the Elderly between dementia and healthy

Not Applicable

Recruiting

• Conditions: Mental and behavioral disorders

• Registration Number: KCT0003328
• Lead Sponsor: Chungbuk National University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 March 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 47

Inclusion Criteria

<Common>
1.Adults over 65

<Cognitive Impairment Group>
1. Subjects with K-MMSE(Korea-Mini Mental Stare Examination) score less than 24
2. Subjects between CDR 0.5-2 points, mild cognitive impairment and mild / moderate dementia

<Normal control group>
1. Subjects with K-MMSE(Korea-Mini Mental Stare Examination) score more than 24
2. Subjects between CDR 0-0.5 points, normal and mild cognitive impairment

*CDR 0.5 Dementia suspects are classified as mild cognitive impairment according to SNSB(Seoul-Neuropsychological Screening Battery) scores. If one or more of the five domains of the SNSB %ile score is less than 15%ile, it is classified as a mild cognitive disorder.

Exclusion Criteria

1.Subjects with Hearing impairment
2.Subjects with visual impairment
3.Subjects with Claustrophobia
4.Subjects with a history of brain surgery
5.Severe dementia with a CDR of 2 points or more
6.Moderate to severe aphasia
7.Mental illnesses other than dementia
8.Subjects with trembling due to Parkinson's disease and other diseases
9. Subjects with nervous or musculoskeletal disorders that can not operate the touch screen by themselves
10.Subjects who have started taking medications for dementia within the last 3 months or who have changed their medication
11. Subjects who can not take MRI due to a medical device implanted in the body, such as artificial heartbeat, cerebrovascular surgery

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Seoul Neuropsychological Screening Battery;Korea Mini Mental State Examination;Clinical Dementia Rating;Change of Brain blood flow (by NIRS);Change of Brain activity (by fMRI)

Secondary Outcome Measures

Name	Time	Method
Barthel-ADL;K-IAD