Improving physical activity and metabolic health in an ageing populatio

Completed

Conditions: veroudering
Healthy Ageing
10018424

Registration Number: NL-OMON34041

Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 235

Inclusion Criteria

Age between 60-70 years
Low level of physical activity at baseline (as assessed by physical activity questionnaire)
motivation to engage in a more active life style
access to PC and knowledge how to use it

Exclusion Criteria

Known diabetes mellitus type I or II
- Severe physical condition that inhibits increase in physical activity
- Use of glucose lowering medication

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary end points<br /><br>• Level of daily activity, as measured using the DirectLife activity monitors,<br /><br>expressed as activity counts per day (cnts/d).<br /><br>• We will use continuous glucose monitoring to assess at least the following<br /><br>parameters of 24-hour glucose rhythms: i) mean glucose level during , ii)<br /><br>standard deviation of all 24 hour glucose measurements, iii) highest peak after<br /><br>a meal (including one standardized oral glucose loading), iv) difference<br /><br>between highest and lowest level, v) nadir glucose.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary end points<br /><br>- Other metabolic and anthropometric parameters, : weight, waist hip ratio,<br /><br>body fat percentage (BIA) and blood pressure will be measured at baseline and<br /><br>at the final visit, and blood sampling for total cholesterol, HDL-cholesterol,<br /><br>triglycerides, fasting glucose, fasting insulin and HbA1c<br /><br>- Well being and perceived health will be assessed by Quality of Life (QoL)<br /><br>SF-36 questionnaire prior to the trial and after the trial<br /><br>- sleep quality will be assessed by the Pittsburg Sleep Quality Index before<br /><br>and after the intervention.</p><br>