Study of Sildenafil in Patient With Heart Failure.

Phase 3

Completed

• Conditions: Congestive Heart Failure

• Registration Number: NCT00309816
• Lead Sponsor: Massachusetts General Hospital

Brief Summary

The purpose of this study is to determine if sildenafil (Viagra) improves exercise tolerance.

Detailed Description

Patients will undergo an exercise stress test. One dose of Sildenafil will then be given, followed by a one hour rest period. A repeat exercise stress test will then be repeated.

Study Timeline

• Study Start: 2001-12
• Study Completion: 2006-02
• Status Verified: 2006-03
• Study First Submitted: 2006-03-30
• Study First Submitted QC: 2006-03-30
• Last Update Submitted: 2006-03-30
• Study First Posted: 2006-04-03
• Last Update Posted: 2006-04-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Age 18 - 75 Ejection fraction <35% Heart failure limited by fatigue and shortness of breath -

Exclusion Criteria

Inability to exercise. Patients with shortness of breath while resting. Patient requiring intravenous medication. Patients taking the following medications: nitroglycerine pill/patch/paste, isordil and Imdur

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Patients will have exercise capacity measured by an exercise stress test before and after one dose of sildenafil.

Trial Locations

Locations (1)

Massachusetts General Hospital; 🇺🇸 Boston, Massachusetts, United States