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临床试验/NCT03310476
NCT03310476已完成不适用

Influence of Resistant Starch in Baked and Boiled Potatoes on Glycemic and Satiety Responses in Overweight Females

Texas Woman's University2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2018年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
2
主要终点
Change in postprandial glucose and insulin concentrations

研究概览

简要总结

Resistant starch (RS) is a type of fiber that has unique digestive properties that can impact overall health including glucose homeostasis and satiety. RS found in potatoes can be increased by using certain cooking methods and serving temperatures. The purpose of this trial will compare the acute glycemic and satiety responses after consuming potatoes differing in RS content that are 1) baked then chilled or 2) boiled and consumed hot in overweight females on two separate occasions.

详细描述

Potatoes are a low-cost, nutrient-dense dietary staple in the U.S. rich in complex carbohydrates, potassium, magnesium, and fiber, but low in fat and sodium. Starch is the main complex carbohydrate found in potatoes that yields glucose to contribute to overall energy needs. Another type of starch found in potatoes is resistant to amylase hydrolysis in the small intestine which is resistant starch (RS). Trials using RS as a functional ingredient (~15-30 g/day) in healthy and overweight adults resulted in improvements in postprandial glucose, insulin sensitivity, satiety hormone response, and subjective satiety. Limited data exists using RS naturally found in commonly consumed foods, such as potatoes. Altering the cooking methods and serving temperatures of potatoes can influence the amount of RS to impact glucose, satiety hormone response, and subjective satiety. Using a cross-sectional, cross-over design, the aim of this study will determine how potatoes 1) baked and chilled or 2) boiled and consumed hot influence postprandial glycemic parameters, satiety hormones (glucagon-like peptide-1, peptide YY, and glucose-dependent insulinotropic polypeptide), subjective satiety, and subsequent energy intake in overweight females.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Overweight and obese (BMI between 28 and 40 kg/m^2)
  • Any race or ethnicity

排除标准

  • Diabetes or other metabolic disorder, cancer, or cardiovascular disease
  • Pregnant or lactating
  • More than 5% weight loss or gain over prior 6 months
  • Following a special diet
  • Sensitivity or aversion to potatoes

研究组 & 干预措施

Baked, consumed chilled potatoes

Experimental

干预措施: Potatoes (Other)

Boiled, consumed hot potatoes

Experimental

干预措施: Potatoes (Other)

结局指标

主要结局

Change in postprandial glucose and insulin concentrations

时间窗: Change in glucose and insulin concentrations collected 15, 30, 60, and 120 minutes following potato intake

Postprandial glucose and insulin concentrations will be compared between interventions

次要结局

  • Change in postprandial peptide YY (PYY, pg/mL) concentrations(Change in PYY concentrations collected 15, 30, 60, and 120 minutes following potato intake)
  • Change in postprandial glucagon-like peptide- 1 (GLP-1, pg/mL) concentrations(Change in GLP-1 concentrations collected 15, 30, 60, and 120 minutes following potato intake)
  • Change in postprandial glucose-dependent insulinotropic peptide (GIP, pg/mL) concentrations(Change in GIP concentrations collected 15, 30, 60, and 120 minutes folllowing potato intake)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mindy Patterson Maziarz

Assistant Professor

Texas Woman's University

研究点 (2)

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