What role do immune cells have in the development and persistence of Sjögren's syndrome? - Role of immune cells in Sjögren's Syndrome.

niversitair Medisch Centrum Utrecht0 个研究点目标入组 400 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•Group 1: Patients (>= 18 yr) with sicca complaints, with a suspicion of Sjögren's syndrome, and that will undergo lipbiopsy as a diagnostic tool
•Group 2: Patients (>= 18 yr), who are diagnosed with Sjögren's syndrome, according to the revised American-European consensus group (Vitali, Bombardieri et al. 2002), with a lymphocytic focus score >=1 on minor salivary gland biopsy. Patients (>= 18 yr), who are diagnosed with non-Sjögren's sicca syndrome, with a lymphocytic focus score of 0 on minor salivary gland biopsy.
•Healthy controls (>= 18 yr), recruited from the Minidonordienst (inhouse blood donating service) of the UMC Utrecht, who are free of the use of immunosuppressive drugs.

•Patients with any other causes of dryness will not be included in this study. Individuals that are not free of the use of immunosuppressive drugs at least 3 months prior to this study.

发起方

niversitair Medisch Centrum Utrecht