NCT02791178Unknown不适用
Plaque Evaluation by Optical Coherence Tomography and Its Association With Microvascular Obstruction in Reperfused STEMI Patients - The POMS Study
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 35
- 试验地点
- 1
- 主要终点
- All cause mortality
研究概览
简要总结
The overall objective of this research proposal is to use OCT to investigate those morphological culprit plaque characteristics associated with the risk of developing MVO in reperfused STEMI patients.
详细描述
The specific research objectives include:
- To use OCT to determine the type of plaque (plaque rupture, plaque erosion or calcified nodule) most associated with the presence and severity of MVO (as measured by IMR and cardiac MRI).
- To use OCT to investigate the relationship between the extent of tissue protrusion and the amount of residual stent thrombus with the presence and severity of MVO (as measured by IMR and cardiac MRI).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed STEMI as per the in-charge consultant based on presenting history, ECG and angiogram findings.
- •< 12 hours of onset of chest pain.
- •Ability to provide informed consent
排除标准
- •Previous myocardial infarction or coronary artery bypass graft surgery
- •Cardiac arrest or cardiogenic shock
- •Inability to advance the OCT catheter or to obtain good image quality
- •Ostial lesions
- •Significant renal impairment
- •Contraindications for cardiac MRI
- •Contraindication for adenosine (for IMR measurement)
结局指标
主要结局
All cause mortality
时间窗: Two years
次要结局
未报告次要终点
研究者
研究点 (1)
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