Dietary proteins and blood pressure-related mechanisms.
- Conditions
- HypertensionHigh blood pressureProteinsHoge bloeddrukHypertensieEiwitten
- Registration Number
- NL-OMON20220
- Lead Sponsor
- Maastricht University
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
1. Men and women;
2. BMI 25-35 kg/m2;
Exclusion Criteria
1. Presence of urinary protein;
2. eGFR < 60 ml/min/1.73 m2;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acute TPR response (derived according to the equation; MAP = CO x TPR) on each clinical investigation day during first 4 hours after consumption of supplements. Mean Arterial Pressure (MAP) and Cardiac Output (CO) will be measured.
- Secondary Outcome Measures
Name Time Method Acute responses on renal sodium excretion, vasodilating factors and vascular function changes on each clinical investigation day during first four hours after consumption of supplements.