se of preoperative desmopressin in preventing bleeding in patients treated with SSRI's.

Completed

• Conditions: disorder primary hemostasis

• Registration Number: NL-OMON25097
• Lead Sponsor: -

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 45

Inclusion Criteria

1. Patients aged over 18 who receive a serotonergic antidepressant (fluvoxamine, fluoxetine, paroxetine, sertraline, venlafaxine, clomipramine, citalopram) at least started two weeks before the surgery;

2. Surgery: orthopedic, abdominal, breast.

Exclusion Criteria

1. No informed consent;

2. Disorder in primary hemostasis;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Peri- and postoperative blood loss.

Secondary Outcome Measures

Name	Time	Method
1. Pre- and postoperative hemoglobin; <br /><br>2. Number of perioperative blood transfusion;<br /><br>3. Perioperative fluid infusion;<br /><br>4. Postoperative drainage.