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Effect of Desmopressin on Bleeding During The Nose Job

Phase 3
Conditions
Rhinoplasty and haemorrhage during the surgery.
Registration Number
IRCT20170120032069N7
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
70
Inclusion Criteria

Volunteers with no age limit who undergo the Rhinoplasty

Exclusion Criteria

Cardiovascular disease
Bleeding disorders
High blood pressure
Allergy to Desmopressin
History of cerebrovascular attack
Seizure

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Bleeding during rhinoplasty surgery. Timepoint: Measuring the amount of bleeding at the end of surgery. Method of measurement: The sucker bottle which is calibrated measures bleeding loss.;View of surgeon on operating field. Timepoint: Measuring surgeon satisfaction at the end of surger. Method of measurement: based on the FROMME-BOEZAART Scale.;The time of surgery. Timepoint: Measuring the time of surgery at the end of surgery. Method of measurement: Duration of surgery from the begining to the end of the surgery.
Secondary Outcome Measures
NameTimeMethod
Bleeding will be measured by the surgeon based on the FROMME-BOEZAART Scale. Timepoint: During the surgery. Method of measurement: Based on this scale, there are five grades in which the surgeon during the surgery scores the bleeding. Grade 0: No bleeding (cadaveric conditions); grade 1: Slight bleeding, no suctioning required; grade 2:Slight bleeding, occasional suctioning required; grade 3:Slight bleeding, frequent suctioning required; bleeding threatens surgical field a few seconds after suction is removed; grade 4:Moderate bleeding, frequent suctioning required, and bleeding threatens surgical field directly after suction is removed; grade 5:Severe bleeding, constant suctioning required; bleeding appears faster than can be removed by suction; surgical field severely threatened and surgery usually not possible.
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