The Effect of Intraoperative Infusion of Dexmedetomidine on Acute and chronic postoperative pain after simple mastectomy

Phase 2

Recruiting

• Conditions: Mastectomy.; Encounter for breast reconstruction following mastectomy; Z42.1

• Registration Number: IRCT20141009019470N90
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 December 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 110

Inclusion Criteria

Patients undergoing simple mastectomy
18-65 years
ASA I& II

Exclusion Criteria

Sensitivity to dexmedetomidine
History of heart failure (EF <40%)
Kidney Disorders (Creatinine greater than 2)
History of liver disease
Psychiatric and cognitive disorders
Chronic pain
Drug and cigarette abuse Psychotropic drugs and forgetfulness
Pregnancy
Alcohol abuse
Arthritis
Chronic use of opioids, hypnotics and non-opioid analgesics,
Having diabetes for more than 10 years
Cases in which the surgeon decides to change the surgical procedure for any reason

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Acute pain. Timepoint: The patient's pain is assessed 24 hours after surgery in the recovery room (on arrival at recovery and at the first and second hours) every 4 hours. Method of measurement: Visual Analogue Scale.;Chronic pain. Timepoint: Three months after surgery. Method of measurement: Brief Pain Inventory.

Secondary Outcome Measures

Name	Time	Method
Total Morphine Consumption. Timepoint: Up to 24 hours after surgery. Method of measurement: Observasion.