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Clinical Trials/NCT06680778
NCT06680778
Recruiting
Not Applicable

The Use of Proa-active Monitoring by Measuring Vital Signs Using a Fitbit for a 3-month Period Before, During, and After Chemotherapy in Patients With Cancer

Erasmus Medical Center1 site in 1 country175 target enrollmentJuly 1, 2025

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cancer
Sponsor
Erasmus Medical Center
Enrollment
175
Locations
1
Primary Endpoint
Variance and normalization of resting heart rate
Status
Recruiting
Last Updated
8 months ago

Overview

Brief Summary

The goal of this single center prospective observational study is to determine the effect of chemotherapy on (the change in) vital parameters. The main question it aims to answer are: Can changes in vital parameters be measured by using a Fitbit in patients with cancer while undergoing chemotherapy. Participants will be asked to wear a Fitbit for the first two cycles of chemotherapy to evaluate the changes in vital parameters.

Detailed Description

The goal of this single center prospective observational study is to determine the effect of chemotherapy on (the change in) vital parameters. The main question it aims to answer are: Can changes in vital parameters be measured by using a Fitbit in patients with cancer while undergoing chemotherapy. Participants will be asked to wear a Fitbit for the first two cycles of chemotherapy to evaluate the changes in vital parameters. Patients will start measuring in the week prior to the first cycle of chemotherapy, target is at least 4 to 7 days before initiation of chemotherapy. Patients were the Fitbit as much as possible, during day and night. Patients continuously carry the Fitbit during the first 3 months of systemic treatment, which tracks their vital signs. At the starting day of the next cycle of chemotherapy patients will have an appointment with one of the researchers to evaluate the use of the Fitbit. Furthermore, it will be checked if a patient has returned to their baseline vital signs.

Registry
clinicaltrials.gov
Start Date
July 1, 2025
End Date
December 31, 2025
Last Updated
8 months ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jason den Duijn

Principal Investigator

Erasmus Medical Center

Eligibility Criteria

Inclusion Criteria

  • Age ≥18 years;
  • Diagnosis of stomach or esophageal cancer with an indication of starting chemotherapy
  • Knowledge how to handle a Fitbit
  • Mastery of Dutch language
  • Able and willing to give written informed consent

Exclusion Criteria

  • Cognitive disorders or severe emotional instability
  • Already participating in an exercise trial

Outcomes

Primary Outcomes

Variance and normalization of resting heart rate

Time Frame: Through study completion, an average of 6 months

Variance and normalization of resting heart rate in bpm over time during chemotherapy

Variance and normalisation of maximum heart rate

Time Frame: Through study completion, an average of 6 months

Variance and normalization of vital parameters maximum heart rate in bpm over time during chemotherapy

Variance and normalisation of minimum heart rate

Time Frame: Through study completion, an average of 6 months

Variance and normalization of minimum heart rate in bpm over time during chemotherapy

Variance and normalisation of heart rate variability

Time Frame: Through study completion, an average of 6 months

Variance and normalization of vital parameters heart rate variability over time during chemotherapy

Variance and normalisation of respiratory rate

Time Frame: Through study completion, an average of 6 months

Variance and normalization of respiratory rate in absolute numbers over time during chemotherapy

Variance and normalisation of blood pressure

Time Frame: Through study completion, an average of 6 months

Variance and normalization of blood pressure in mmHG over time during chemotherapy

Variance and normalisation of step count

Time Frame: Through study completion, an average of 6 months

Variance and normalization of step count in absolute numbers over time during chemotherapy

Variance and normalisation of blood oxygen saturation

Time Frame: Through study completion, an average of 6 months

Variance and normalization of blood oxygen saturation in percentage over time during chemotherapy

Variance and normalisation of sleep time

Time Frame: Through study completion, an average of 6 months

Variance and normalization of sleep time in hours over time during chemotherapy

Variance and normalisation of sleep quality

Time Frame: Through study completion, an average of 6 months

Variance and normalization of sleep quality on a scale from 1 to 10 over time during chemotherapy

Secondary Outcomes

  • Contact with healthcare provider(Through study completion, an average of 6 months)
  • emergency department visits(Through study completion, an average of 6 months)
  • Toxicity(Through study completion, an average of 6 months)
  • Dose Modification of chemotherapy(Through study completion, an average of 6 months)

Study Sites (1)

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