Comparison of Effects of Combined Spinoepidural and General Anesthesia Effects on Incidence of Postoperative Complications Following Total Knee Arthroplasty
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Arthroplasty, Replacement, Knee
- Sponsor
- Ufuk University
- Enrollment
- 130
- Locations
- 1
- Primary Endpoint
- Death
- Last Updated
- 7 years ago
Overview
Brief Summary
The aim of this study is to investigate the effect of combined spinoepidural and general anesthesia on the incidence of postoperative complications following total knee arthroplasty
Detailed Description
Total knee arthroplasty is known to cause complications (pulmonary thromboembolism, acute kidney injury, arryhthmias and infection). The investigators aimed to study the effects of two different anesthesia techniques, i.e. combined spinoepidural anesthesia and general anesthesia on the incidence of postoperative complications such as arrhythmia, pulmonary thrombeoembolism, infection, acute kidney injury and mortality.
Investigators
Perihan Ekmekçi
Primary Investigator
Ufuk University
Eligibility Criteria
Inclusion Criteria
- •Patients scheduled to undergo elective unilateral total knee arthroplasty
Exclusion Criteria
- •Patient refusal
- •Scheduled for bilateral or unilateral unicondylar knee arthroplasty
- •Known history of allergy to drugs used in the study
- •Severe systemic disease
- •Morbid obesity (BMI\>30)
- •History of renal dysfunction
Outcomes
Primary Outcomes
Death
Time Frame: Postoperative sixth week
Number of participants with mortality
Pulmonary Thromboembolism
Time Frame: Postoperative sixth week
Number of participants with new onset pulmonary thromboembolism
Infection
Time Frame: Postoperative sixth week
Number of participants with new onset infection
Arryhthmia
Time Frame: Postoperative sixth week
Number of participants with new onset arryhthmia requiring treatment
Acute Kidney Injury
Time Frame: Postoperative sixth week
Number of participants with new onset acute kidney injury