Markers of endothelial activation and damage in haematological patients in relation to efficacy of transfusion support: a pilot study

Completed

• Conditions: Sickle cell disease; Haematological Disorders; Sickle-cell disorders

• Registration Number: ISRCTN35472475
• Lead Sponsor: Sanquin Blood Bank South West Region (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-03-07
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

1. Age greater than 18 years
2. Haemato-oncological disease
3. Sickle cell disease
4. Informed consent

Exclusion Criteria

1. Active cardiovascular disease
2. Recent thrombo-embolism

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Efficacy of platelet transfusion or red blood cell exchange transfusion in haemato-oncological patients and sickle cell patients, respectively, in relation to several endothelial activation markers.

Secondary Outcome Measures

Name	Time	Method
o secondary outcome measures