Pathophysiological mechanisms in the development of anal fistula. Oral antibiotics after anal abscess drainage to diminish perianal Fistula Formation: a multicenter, randomized, observer-blind, placebo-controlled clinical trial. - O.F.F.

Hospital Universitari Germans Trias i Pujol0 个研究点目标入组 210 人开始时间: 2021年2月1日最近更新: 2021年5月10日

适应症

试验速览

暂无简介。

•18 years or more
•Both genders
•Clinical diagnosis of anal abscess (acute inflammatory signs and presence of a purulent collection in the perianal area) seen or confirmed through punction aspiration of purulent material with needle.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 150
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 60

•Inflammatory bowel disease
•Anal surgical history
•Anal fistula alredy konwn
•Anal carcinoma and/or pelvic radiotherapy
•Anal trauma history
•horse shoe abscess
•Inmunodeficiency, diabetes, pregnancy or lactation, heart valve disease or prosthetic valve carriers
•Spontaneous drainage of abscess
•Antibiotics use
•Contraindications of ciprofloxacin according to SPC (hypersensitivity to the active principle, or to other quinolones or to any of the excipients; concomitant administration of ciprofloxacin and tizanidine)
•- Contraindications of metronidazole according to SPC (hypersensitivity to imidazoles or to any of the excipients)
•-Pregnancy and lactation

发起方

Hospital Universitari Germans Trias i Pujol