ACTRN12612000987864终止4 期
The effect of Probenecid-Allopurinol combined therapy compared to higher dose Allopurinol on serum uric acid levels in poorly controlled gout patients: A Pilot Prospective Study.
Tauranga Hospital0 个研究点目标入组 30 人开始时间: 2012年9月13日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 90 Years（—）
- 性别
- All
入选标准
- •Gout defined as per the American College of Rheumatology preliminary criteria. Any patient meeting this definition, either from a primary or secondary care source.
- •- Already receiving long-term maintenance therapy of allopurinol 300mg once a day for more than 1 month, yet still having uncontrolled SUA levels (defined as SUA>0.36).
- •- Consents to alteration in medications/doses
- •- Is able to take medications that are not confined to ‘blister packs’ – (pre-formed packs from pharmacist).
排除标准
- •- Known hypersensitivity to Probenecid, or higher dose Allopurinol
- •- Estimated glomerular filtration rate (eGFR) >60ml/min
- •- Known renal/ureteric stones
- •- Gout flare less than 2 weeks prior to entering the trial.
研究者
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