Neuroaxial Blokade and Blood Pressure

Not Applicable

• Conditions: Hypovolemia

• Registration Number: NCT00435422
• Lead Sponsor: Rigshospitalet, Denmark

Brief Summary

The effect of individualized fluid optimization during neuroaxial blockade has not been evaluated. The investigators evaluated if if Stroke decrease 15 min after activation of neuroaxial blockade and whether SV could be optimized to pre activation values.

Detailed Description

The purpose of this study is to evaluate SV maximization with aid of the LiDCO system which is a minimal invasive technique only requiring a venous and arterial line. We thereby attempt to cover the specific individual fluid deficit induced by neuroaxial blockade.

Study Timeline

• Study First Submitted: 2007-02-14
• Study First Submitted QC: 2007-02-14
• Study First Posted: 2007-02-15
• Status Verified: 2009-02
• Study Start: 2010-01
• Last Update Submitted: 2010-03-24
• Last Update Posted: 2010-03-25
• Primary Completion: 2010-05
• Study Completion: 2010-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Neuroaxial blockade (thoracic)

Exclusion Criteria

• Weight below 40 kg
• Lithium therapy
• Type I diabetes or type II requiring insulin

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Stroke volume	15 min after blockade

Secondary Outcome Measures

Name	Time	Method
Brain oxygenation, cardiac output, TPR, NIRS, BP	15 min after blockade

Trial Locations

Locations (1)

Rigshospitalet; 🇩🇰 Copenhagen, Denmark