11C- metomidate positron emission tomography (PET) scanning for Conn's syndrome

Phase 4

Completed

• Conditions: Topic: Metabolic and Endocrine; Subtopic: Metabolic and Endocrine (all Subtopics); Disease: Metabolic & Endocrine (not diabetes); Nutritional, Metabolic, Endocrine; Conn's adenoma

• Registration Number: ISRCTN58267591
• Lead Sponsor: Cambridge University Hospitals NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-05-12
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Male or female
2. Aged 18 years or over
3. Suspected Conn's syndrome or suspected adrenal hyperplasia or healthy with non-functional adenoma

Exclusion Criteria

1. Inability to give informed consent
2. Heart failure
3. Women of childbearing potential not using contraception
4. Pregnant or breast feeding women

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The sensitivity of 11C-metamidate PET/CT scanning for detecting Conn's adenoma

Secondary Outcome Measures

Name	Time	Method
1. The specificity of 11C-metomidate PET/CT scanning for detecting Conn's Syndrome<br>2. To determine the suppression protocol that leads to the best sensitivity of 11C-metomidate PET/CT scanning for detecting Conn's Syndrome