Breast Artery Calcification as A Surrogate Marker for Vascular Calcification in Chronic Kidney Disease

Completed

• Conditions: Presence of BAC has been reported in CKD, but limited performance of BAC for screening vascular calcification in patients with CKD.; Breast artery calcification, coronary artery calcification, chronic kidney disease

• Registration Number: TCTR20220319003
• Lead Sponsor: Division of Nephrology, Department of Medicine, Phramongkutklao Hospital

Brief Summary

The presence and severity of BAC is markedly increased in advanced CKD and it is significantly associated with older age and lower GFR. Combination of BAC and AAC performed good performance in predicting a coronary calcification, especially in advanced CKD.

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-03-09
• Study Start: 2022-03-19
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 103

Inclusion Criteria

Age > 40 years
- Women
- eGFR <90 ml/min/1.73m2
- Signed informed consent

Exclusion Criteria

- Advanced stage breast cancer
- Presence of coronary artery bypass grafting or coronary artery stent
- Contraindication to mammogram or CT coronary

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Breast artery calcification (BAC) Have data record for abdominal aortic calcification (AAC) and coronary arterial calcification (CAC) within 1 year mammography

Secondary Outcome Measures

Name	Time	Method
Associated factors of BAC N/A laboratory record,AAC Have data record for BAC and CAC within 1 year Lateral plain film abdomen