Association of Breast Arterial Calcification with Cardiovascular Disease

Not Applicable

• Conditions: Cardiovascular Disease; Breast Arterial Calcification; Cardiovascular - Coronary heart disease; Cardiovascular - Diseases of the vasculature and circulation including the lymphatic system; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12621001407886
• Lead Sponsor: Monash Cardiovascular Research Centre, Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-10-19
• Last Update Posted: 26 October 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

1. Have had breast mammography and clinically indicated Coronary Computed Tomography Angiography (CCTA) at Monash Health.
2. Agreeable to undergo single research CCTA at Monash Health.
3. Agree to collection of blood for storage

Exclusion Criteria

1. Inability to provide informed consent or unwillingness to undergo CCTA
2. Previous allergic reaction to contrast media.
3. Severe renal impairment (eGFR <30mL/min).
4. Asthma or Chronic Respiratory Disease in patients who may need beta-blockade to lower heart rate.
5. Women who may be pregnant (premenopausal women will undergo pregnancy testing).

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presence of coronary artery plaque [At time of research cardiac CT];Composite of coronary artery plaque quantity and composition (e.g. calcified plaque, high risk plaque) [At time of research cardiac CT]

Secondary Outcome Measures

Name	Time	Method
Volume of peri-coronary adipose tissue [At time of research cardiac CT];Density of peri-coronary adipose tissue [At time of research cardiac CT ]