Lung Perfusion With Oxygenated Blood During Aortic Clamping

Not Applicable

Completed

• Conditions: Postoperative Pulmonary Dysfunction
• Interventions: Procedure: lung perfusion; Procedure: no lung perfusion

• Registration Number: NCT01186510
• Lead Sponsor: Johann Wolfgang Goethe University Hospital

Brief Summary

Pulmonary dysfunction presumably linked to an inflammatory response is frequent after cardiac operations using cardiopulmonary bypass (CPB) and pulmonary hypoperfusion.

Aim of the study: To evaluate the protective effect of continuous pulmonary perfusion with oxygenated blood during aortic crossclamping on the inflammatory response.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-08
• Study First Submitted: 2010-08-19
• Study First Submitted QC: 2010-08-20
• Study First Posted: 2010-08-23
• Primary Completion: 2012-11
• Study Completion: 2012-11
• Status Verified: 2013-06
• Last Update Submitted: 2013-06-03
• Last Update Posted: 2013-06-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Age 18-80 ys
• Cardiopulmonary bypass procedure
• FEV1 <80%
• COPD >II

Exclusion Criteria

• Emergency cases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Lung perfusion	lung perfusion	-
no lung perfusion	no lung perfusion	-

Primary Outcome Measures

Name	Time	Method
Inflammatory marker	5 days

Trial Locations

Locations (1)

Goethe University; 🇩🇪 Frankfurt am Main, Germany