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Clinical Trials/NCT04082208
NCT04082208
Unknown
Not Applicable

Use of High Flow Nasal Cannula in Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) Under Sedation. Comparative, Randomized Study of Two Health Products Approved by the Community

Hospital Clinic of Barcelona1 site in 1 country172 target enrollmentFebruary 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Patient Population Submitted to ERCP
Sponsor
Hospital Clinic of Barcelona
Enrollment
172
Locations
1
Primary Endpoint
Desaturation during ERCP
Last Updated
6 years ago

Overview

Brief Summary

The expected results with this study are that high flow devices (LAF) provide adequate respiratory support during the performance of ERCP under deep sedation, reducing episodes of desaturation, hypoventilation and airway obstruction compared to low flow devices ( nasal glasses).

Detailed Description

Deep sedation performed during the ERCP technique associates an increased risk of decrease in Sat02%, hypercapnia and airway obstruction with consequences ranging from interruption or suspension of the technique to complications that may put the patient's life at risk . High flow devices (HF) due to the pressurization capacity of the airway and the reduction of anatomical dead space will favor a better gas exchange compared to low flow devices (LF), which will manifest clinically with a reduction in episodes of decrease of Sat02% and a decrease in carbon dioxide levels. The main objective of the study is to demonstrate that the use of high flow devices (HF) decreases the episodes of desaturation (defined as Sat02 ≤ 90% measured through pulse oximetry) that occur during the performance of ERCP under deep sedation compared to Low flow devices (LF) with equal Inspiratory oxygen fraction (Fi02) in both cases. The expected results with this study are that high flow devices (LAF) provide adequate respiratory support during the performance of ERCP under deep sedation, reducing episodes of desaturation, hypoventilation and airway obstruction compared to low flow devices ( nasal glasses).

Registry
clinicaltrials.gov
Start Date
February 1, 2020
End Date
January 1, 2021
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

JULIA MARTÍNEZ OCÓN

Anesthesiologist

Hospital Clinic of Barcelona

Eligibility Criteria

Inclusion Criteria

  • Patients Age over ≥18 years. Willing to participate

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Desaturation during ERCP

Time Frame: 2 years

Demonstrate that the use of high flow devices (HF) decreases episodes of desaturation (defined as Sat02 ≤ 90% measured by pulse oximetry) that occur during the performance of ERCP under deep sedation compared to low flow devices ( LF).

Secondary Outcomes

  • CO2 during ERCP(2 years)

Study Sites (1)

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